Pair page
Testagen with Thymalin
Mechanism-tag overlap and published literature for Testagen and Thymalin, pulled verbatim from each Kalios compound profile. Kalios is a literature reference, not a recommendation.
Mechanism overlap
Mechanism tags are verbatim labels on each compound's profile. Generic tags ("peptide", "small-molecule", "research-chemical") are excluded from this overlap view. Tags are descriptive — not an inference about combined effect.
khavinson-testicular-bioregulator
thymic-polypeptide-bioregulator-complex
Co-administration notes from the literature
Verbatim summary text pulled from each compound's profile data. Researchers studying Testagen and Thymalin have published these mechanism-level observations. Not a co-administration recommendation.
Thymic peptide complex. Part of the comprehensive Khavinson protocol. Addresses the immune-aging dimension alongside Testagen's testicular dimension.
Quick facts
Testagen
Thymalin
Literature table
Classified references from each compound profile. Click a column header to sort. Click a PMID to open PubMed. Findings are quoted verbatim from each profile's literature_summary; nothing here is added or interpreted.
| Year | Compound | Source | Finding |
|---|---|---|---|
| 2012 | Testagen | Khavinson VK, Solovyev AY, Zhilinskiy DV, Shataeva LK, Vanyushin BF. Effect of peptides on the proliferative activity of cells of rat pituitary anterior lobe in organotypic culture. Bull Exp Biol Med. 2012;153(1):148-151. PMID: 22808512. PMID 22808512 | preclinical, in vivo |
| 2011 | Testagen | Fedoreyeva LI, Kireev II, Khavinson VK, Vanyushin BF. Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA. Biochemistry (Mosc). 2011;76(11):1210-1219. PMID: 221… PMID 22118470 | preclinical, in vitro |
| 2021 | Testagen | Khavinson VK, Popovich IG, Linkova NS, Mironova ES, Ilina AR. Peptide regulation of cell differentiation, gene expression, and protein synthesis. Bull Exp Biol Med. 2021;170(5):707-711. (Review including testicular and other tissue-specific peptides.) | mechanism / discovery |
| 2003 | Testagen | Khavinson VK, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003;135(6):590-592. PMID: 12937678. (Representative Khavinson-group mechanistic paper; establishes the methodological style.) PMID 12937678 | mechanism / discovery |
| 2002 | Testagen | Khavinson VK. Peptides and Ageing. Neuroendocrinol Lett. 2002;23 Suppl 3:11-144. PMID: 12374906. (Foundational review of the Khavinson peptide bioregulator framework.) PMID 12374906 | review |
| 2026 | Testagen | ClinicalTrials.gov. Search: "Testagen" or "KEDG peptide" returns no registered trials. Accessed April 2026. | regulatory / registry |
| 2025 | Testagen | FDA. Bulk Drug Substances Nominated for Use in Compounding under Section 503A of the Federal Food, Drug, and Cosmetic Act. FDA.gov. Updated 2025–2026 (Testagen / KEDG not listed). | regulatory / registry |
| 2025 | Testagen | WADA. 2025 Prohibited List. World Anti-Doping Agency. (Testagen not specifically named.) | regulatory / registry |
| 2020 | Testagen | Khavinson VK, Linkova NS, Ashapkin VV, Ryzhak GA. Peptide Regulation of Aging: 40 Years of Research. Bull Exp Biol Med. 2020;170(2):190-193. PMID: 33263832. PMID 33263832 | bioregulator literature |
| 2020 | Testagen | Khavinson VK. Peptide drugs: their role in fundamental and applied medicine. Advances in Gerontology. 2020 Khavinson group series. | bioregulator literature |
| 2011 | Testagen | Korkushko OV, Khavinson VKh, Shatilo VB, Antonyk-Sheglova IA. Peptide geroprotector from the pituitary gland inhibits rapid aging of elderly people: results of 15-year follow-up study. Bull Exp Biol Med. 2011;151(3):366-369. PMID: 22451891. PMID 22451891 | bioregulator literature |
| 2010 | Testagen | Anisimov VN, Khavinson VKh. Peptide bioregulation of aging: results and prospects. Biogerontology. 2010;11(2):139-149. PMID: 19415510. PMID 19415510 | bioregulator literature |
| 2021 | Thymalin | Khavinson VK, Kuznik BI, Tarnovskaya SI, Linkova NS. Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19. Stem Cell Rev Rep. 2021 Feb;17(1):285-290. doi: 10.1007/s12015-020-10087-6. PMID: 33575961. (Re… PMID 33575961 | human study |
| 2020 | Thymalin | Khavinson V, Linkova N, Dyatlova A, Kuznik B, Umnov R. Peptides: Prospects for Use in the Treatment of COVID-19. Molecules. 2020 Sep 24;25(19):4389. doi: 10.3390/molecules25194389. PMID: 32987757. (Computational and mechanistic review of Khavinson short peptides — including the… PMID 32987757 | human study |
| 2020 | Thymalin | Khavinson VK, Kuznik BI, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimova SV, Ryzhak GA, Potyomkin VV, Saginbaev UR. Effect of thymalin on adaptive immunity in complex therapy for patients with COVID-19. Klinicheskaya Meditsina (Russian Journal). 2020;98(8):593-… | human study |
| 2020 | Thymalin | Lukyanov SA, Kuznik BI, Shapovalov KG, Khavinson VK, Smolyakov YN, et al. Thymalin as a Potential Alternative in the Treatment of Severe Acute Respiratory Infection Associated with SARS-CoV-2. Int J Immunol Immunother. 2020;7:055. (Severe-COVID-19 case treated with Thymalin 10 m… | human study |
| 1986 | Thymalin | Kuznik BI, Makhakova GCh, Morozov VG, Pisarevskaia LI, Khavinson VKh. [Effect of thymalin on thrombocyte aggregation and the antiaggregation activity of the vascular wall in intact and thymectomized rats]. Biull Eksp Biol Med. 1986 Aug;102(8):200-202. Russian. PMID: 3754821. (Ea… PMID 3754821 | preclinical, in vivo |
| 1982 | Thymalin | Anisimov VN, Khavinson VKh, Morozov VG. Carcinogenesis and aging. IV. Effect of low-molecular-weight factors of thymus, pineal gland and anterior hypothalamus on immunity, tumor incidence and life span of C3H/Sn mice. Mech Ageing Dev. 1982 Jul;19(3):245-258. doi: 10.1016/0047-63… | preclinical, in vivo |
| 2022 | Thymalin | Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, Mironova E, Pulcini R, Robuffo I, Bologna G, Simeone P, Lanuti P, Guarnieri S, Trofimova S, Procopio AD, Toniato E. Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macr… PMID 35408963 | preclinical, in vitro |
| 2020 | Thymalin | Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaya TV, Ivko OM. Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells. Bull Exp Biol Med. 2020 Nov;170(1):118-122. doi: 10.1007/s10517-020-05016-z. PMID: 33237528. (In vitro demonstrati… PMID 33237528 | preclinical, in vitro |
| 2016 | Thymalin | Linkova NS, Drobintseva AO, Orlova OA, Kuznetsova EP, Polyakova VO, Kvetnoy IM, Khavinson VK. Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro. Bull Exp Biol Med. 2016 May;161(1):175-178. doi: 10.1007/s10517-016-3370-x. PMID: 27259484. (Khavinson short… PMID 27259484 | preclinical, in vitro |
| 2017 | Thymalin | Khavinson V, Popovich I. Short Peptides Regulate Gene Expression, Protein Synthesis and Enhance Life Span. In: Vaiserman AM (ed.). Anti-aging Drugs: From Basic Research to Clinical Practice. RSC Drug Discovery Series No. 57. Royal Society of Chemistry; 2017. Chapter 20, pp. 496–… | mechanism / discovery |
| 2016 | Thymalin | Khavinson VK, Lin'kova NS, Tarnovskaya SI. Short Peptides Regulate Gene Expression. Bull Exp Biol Med. 2016 Nov;162(2):288-292. doi: 10.1007/s10517-016-3596-7. PMID: 27909961. (Khavinson group's short-peptide DNA-binding / gene-expression-regulation hypothesis, the mechanistic f… PMID 27909961 | mechanism / discovery |
| 2021 | Thymalin | Khavinson VK, Linkova NS, Kvetnoy IM, Kvetnaia TV, Polyakova VO, Ashapkin VV. The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity. Front Pharmacol. 2021;12:716947. doi: 10.3389/fphar.2021.716947. PMC8365293. (Narrative review summarizing 6–12-ye… | review |
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Frequently asked
Have Testagen and Thymalin been studied together?
Researchers have published mechanistic-level co-administration discussion of Testagen and Thymalin. No human co-administration trials are catalogued in the Kalios profiles. The pair page lists each compound's classified literature; full citations sit on each individual profile.
What mechanisms do Testagen and Thymalin share?
Testagen and Thymalin do not share a specific mechanism tag on their Kalios profiles. They appear on the same pair page because at least one profile lists the other in its co-administration data.
What is the FDA status of Testagen and Thymalin?
Testagen: Not approved; research-only. Thymalin: Not approved (US). FDA-status text is pulled verbatim from each compound profile. See /fda-pcac-2026.html for the broader FDA Pharmacy Compounding Advisory Committee context.
Where can I find the full research on Testagen and Thymalin?
Full citation lists, dosing tables from the literature, reconstitution data, and the FDA / WADA status are on the individual compound profiles: the Testagen profile and the Thymalin profile. The Kalios Stack Research Tool hub lists every compound covered.
Last updated: April 2026